Publications

Link to publication list:

https://www.ncbi.nlm.nih.gov/pubmed/?term=mario+f+feldman

Selected publications:

• Dual membrane-spanning anti-sigma factors regulate vesiculation in Bacteroides thetaiotaomicron. Evan J. Pardue, Mariana G. Sartorio, Biswanath Jana, Nichollas E. Scott, Wandy L. Beatty, Juan C. Ortiz-Marquez, Tim Van Opijnen, Fong-Fu Hsu, Robert F. Potter, Mario F. Feldman. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2321910121. doi: 10.1073/pnas.2321910121. Epub 2024 Feb 29.
• The tRNA methyltransferase TrmB is critical for Acinetobacter baumannii stress responses and pulmonary infection. Jenna C. McGuffey, Clay D. Jackson-Litteken, Gisela Di Venanzio, Aubrey A. Zimmer, Jessica M. Lewis, Jesus S. Distel, Kyusik Q. Kim, Hani S. Zaher, Juan Alfonzo, Nichollas E. Scott, Mario F. Feldman. mBio. 2023 Oct 31;14(5):e0141623. doi: 10.1128/mbio.01416-23. Epub 2023 Aug 17. 
• Human gut bacteria tailor extracellular vesicle cargo for the breakdown of diet- and host-derived glycans. Mariana G Sartorio, Evan J Pardue, Nichollas E Scott, Mario F Feldman. Proc Natl Acad Sci USA. 2023 Jul 4;120(27):e2306314120. doi: 10.1073/pnas.2306314120. Epub 2023 Jun 26.
• Replicative Acinetobacter baumannii strains interfere with phagosomal maturation by modulating the vacuolar pH. Jesus S Distel, Gisela Di Venanzio, Joseph J Mackel, David A Rosen, Mario F Feldman. PLoS Pathog. 2023 Jun 9;19(6):e1011173. doi: 10.1371/journal.ppat.1011173. eCollection 2023 Jun.
• Catheterization of mice triggers resurgent urinary tract infection seeded by a bladder reservoir of Acinetobacter baumannii. Jennie E Hazen, Gisela Di Venanzio, Scott J Hultgren, Mario F Feldman. 2023 Jan 11;15(678):eabn8134. doi: 10.1126/scitranslmed.abn8134. Epub 2023 Jan 11.
• InvL, an Invasin-Like Adhesin, Is a Type II Secretion System Substrate Required for Acinetobacter baumannii Uropathogenesis. Jackson-Litteken CD, Di Venanzio G, Le NH, Scott NE, Djahanschiri B, Distel JS, Pardue EJ, Ebersberger I, Feldman MF. mBio. 2022 Jun 28;13(3):e0025822. doi: 10.1128/mbio.00258-22. Epub 2022 May 31.
• The Phenylacetic Acid Catabolic Pathway Regulates Antibiotic and Oxidative Stress Responses in Acinetobacter. Hooppaw AJ, McGuffey JC, Di Venanzio G, Ortiz-Marquez JC, Weber BS, Lightly TJ, van Opijnen T, Scott NE, Cardona ST, Feldman MF. mBio. 2022 Jun 28;13(3):e0186321. doi: 10.1128/mbio.01863-21. Epub 2022 Apr 25.
• Lipidomics Analysis of Outer Membrane Vesicles and Elucidation of the Inositol Phosphoceramide Biosynthetic Pathway in Bacteroides thetaiotaomicron. Sartorio MG, Valguarnera E, Hsu FF, Feldman MF. Microbiol Spectr. 2022 Feb 23;10(1):e0063421. doi: 10.1128/spectrum.00634-21. Epub 2022 Jan 26.
• Plasmid-Encoded H-NS Controls Extracellular Matrix Composition in a Modern Acinetobacter baumannii Urinary Isolate. Benomar S, Di Venanzio G, Feldman MF.J Bacteriol. 2021 Oct 12;203(21):e0027721. doi: 10.1128/JB.00277-21. Epub 2021 Aug 16.
• Formylglycine-Generating Enzyme-Like Proteins Constitute a Novel Family of Widespread Type VI Secretion System Immunity Proteins. Lopez J, Le NH, Moon KH, Salomon D, Bosis E, Feldman MF.J Bacteriol. 2021 Oct 12;203(21):e0028121. doi: 10.1128/JB.00281-21. Epub 2021 Aug 16.
• Bacterial Outer Membrane Vesicles: From Discovery to Applications. Sartorio MG, Pardue EJ, Feldman MF, Haurat MF.Annu Rev Microbiol. 2021 Oct 8;75:609-630. doi: 10.1146/annurev-micro-052821-031444. Epub 2021 Aug 5.
• Killing of Gram-negative and Gram-positive bacteria by a bifunctional cell wall-targeting T6SS effector. Le NH, Pinedo V, Lopez J, Cava F, Feldman MF.Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2106555118. doi: 10.1073/pnas.2106555118.
• Modern Acinetobacter baumannii clinical isolates replicate inside spacious vacuoles and egress from macrophages. Sycz G, Di Venanzio G, Distel JS, Sartorio MG, Le NH, Scott NE, Beatty WL, Feldman MF.PLoS Pathog. 2021 Aug 9;17(8):e1009802. doi: 10.1371/journal.ppat.1009802.
• The Glycoprotease CpaA Secreted by Medically Relevant Acinetobacter Species Targets Multiple O-Linked Host Glycoproteins. Haurat MF, Scott NE, Di Venanzio G, Lopez J, Pluvinage B, Boraston AB, Ferracane MJ, Feldman MF.mBio. 2020 Oct 6;11(5):e02033-20. doi: 10.1128/mBio.02033-20.
• Peptidoglycan editing provides immunity to Acinetobacter baumannii during bacterial warfare. Le NH, Peters K, Espaillat A, Sheldon JR, Gray J, Di Venanzio G, Lopez J, Djahanschiri B, Mueller EA, Hennon SW, Levin PA, Ebersberger I, Skaar EP, Cava F, Vollmer W, Feldman MF.Sci Adv. 2020 Jul 22;6(30):eabb5614. doi: 10.1126/sciadv.abb5614.
• The Tip of the VgrG Spike Is Essential to Functional Type VI Secretion System Assembly in Acinetobacter baumannii. Lopez J, Ly PM, Feldman MF mBio. 2020 Jan 14;11(1). pii: e02761-19. doi: 10.1128/mBio.02761-19.
• A Broad Spectrum Protein Glycosylation System Influences Type II Protein Secretion and Associated Phenotypes in Vibrio cholerae. Vorkapic D, Mitterer F, Pressler K, Leitner DR, Anonsen JH, Liesinger L, Mauerhofer LM, Kuehnast T, Toeglhofer M, Schulze A, Zingl FG, Feldman MF, Reidl J, Birner-Gruenberger R, Koomey M, Schild S. Front Microbiol. 2019 Dec 3;10:2780. doi: 10.3389/fmicb.2019.02780.
• A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae. Feldman MF, Mayer Bridwell AE, Scott NE, Vinogradov E, McKee SR, Chavez SM, Twentyman J, Stallings CL, Rosen DA, Harding CM. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18655-18663. doi: 10.1073/pnas.1907833116.
• The structure of Acinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone-substrate interaction. Urusova DV, Kinsella RL, Salinas ND, Haurat MF, Feldman MF, Tolia NH. J Biol Chem. 2019 Sep 6;294(36):13344-13354. doi: 10.1074/jbc.RA119.009805.
• Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes. Di Venanzio G, Flores-Mireles AL, Calix JJ, Haurat MF, Scott NE, Palmer LD, Potter RF, Hibbing ME, Friedman L, Wang B, Dantas G, Skaar EP, Hultgren SJ, Feldman MF. Nat Commun. 2019 Jun 24;10(1):2763. doi: 10.1038/s41467-019-10706-y.
• Uncovering the mechanisms of Acinetobacter baumannii virulence. Harding CM, Hennon SW, Feldman MF. Nat Rev Microbiol. 2018; 16(2):91-102. doi: 10.1038/nrmicro.2017.148.
• Defining the interaction of the protease CpaA with its type II secretion chaperone CpaB and its contribution to virulence in Acinetobacter species. Kinsella RL, Lopez J, Palmer LD, Salinas ND, Skaar EP, Tolia NH, Feldman MF. J Biol Chem. 2017; 292(48):19628-19638. doi: 10.1074/jbc.M117.808394.
• Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems. Harding CM, Pulido MR, Di Venanzio G, Kinsella RL, Webb AI, Scott NE, Pachón J, Feldman MF. J Biol Chem. 2017; 292(22):9075-9087. doi: 10.1074/jbc.M117.781575.
• Genetic Dissection of the Type VI Secretion System in Acinetobacter and Identification of a Novel Peptidoglycan Hydrolase, TagX, Required for Its Biogenesis. Weber BS, Hennon SW, Wright MS, Scott NE, de Berardinis V, Foster LJ, Ayala JA, Adams MD, Feldman MF. MBio. 2016; 7(5). pii: e01253-16. doi: 10.1128/mBio.01253-16.
• Medically Relevant Acinetobacter Species Require a Type II Secretion System and Specific Membrane-Associated Chaperones for the Export of Multiple Substrates and Full Virulence. Harding CM, Kinsella RL, Palmer LD, Skaar EP, Feldman MF. PLoS Pathog. 2016; 12(1):e1005391. doi: 10.1371/journal.ppat.1005391.
• A multidrug resistance plasmid contains the molecular switch for type VI secretion in Acinetobacter baumannii. Weber BS, Ly PM, Irwin JN, Pukatzki S, Feldman MF. Proc Natl Acad Sci U S A. 2015; 112(30):9442-7. doi: 10.1073/pnas.1502966112.
• Identification of a general O-linked protein glycosylation system in Acinetobacter baumannii and its role in virulence and biofilm formation. Iwashkiw JA, Seper A, Weber BS, Scott NE, Vinogradov E, Stratilo C, Reiz B, Cordwell SJ, Whittal R, Schild S, Feldman MF. PLoS Pathog. 2012; 8(6):e1002758. doi: 10.1371/journal.ppat.1002758